I have to click yes on automatic daily tasks for them to run.

[nandu2u2]

I assume this is the case for the weekly and monthly too (I have not seen a weekly show up yet but it has been about a month). I just used the default installed tasks that came with the installer.
Windows 7 pro x64

[jeroen]

MyDefrag does not show a "yes" thing. In other words, whatever "yes" thing you are seeing is not coming from MyDefrag. Perhaps it is the Windows UAC protection. Make sure that the task's properties are configured so it will run on a userid with administrator privileges.

[nandu2u2]

Yeah, it was Windows. I checked the task scheduler and set it to run with highest privileges and added my password. I think that will fix it hopefully if anyone else is wondering. Thanks