I don't tink that moving files into zones would bring any speed improvement. In this case, you have to make a huge number of zones after the layout.ini zone. System files, program files for each program. Then it might give a significant speed improvement without sorting. Remember that you should not make too much gaps between zones.
So I sort the layout.ini + program hints + regular files. Together they aren't such big. The spacehog zone is the biggest. I blame the winsxs directory.
Did not I say Mydefrag does not provide an efficient and convenient solution for microzone file grouping yet ?
But saying it would not provide performance gain as almost like saying that about file sorting.
According to some interesting articles, monitoring 60000 workstation for 5 years, median file size is 10-50kB. Being such small, needed file access time is in average 1-1.5 order longer than file transfer time, so file grouping makes even more sense than file placing.
Most of the gain of file sorting is not because of sorting, but because of grouping, being the only easily usable file grouping method. But grouping only would give higher gain/price than grouping by sorting.
Multizoning can be performed by a complicated scripts hard to maintain, slow to precess if there are complex booleans,
without possibilities to avoid extra gaps between microzones.